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Home > Protein Information

Coagulation Factor VIII

Human Coagulation Factor VIII (F8) is One of the clotting factors, the function for this protein is:Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa. It’s including 2351 amino acid, and it usually cleaved into 4 chains:
Factor VIIIa heavy chain, 200 kDa isoform
Factor VIIIa heavy chain, 92 kDa isoform
Factor VIII B chain
Factor VIIIa light chain
To study the concentration in human samples, we need and elisa kit, that’s special for detect the F8 in human plasma and other biological fluids.
A human factor VIII ELISA kit is a type of ELISA assay designed to measure the amount of factor VIII protein in human samples such as plasma and serum.
This kit typically includes antibodies specific to human factor VIII and uses an enzyme-linked detection method to generate a measurable signal. The results of the ELISA can provide information on the levels of factor VIII in a sample, which can be useful in the diagnosis and management of bleeding disorders, as well as in research applications to study the coagulation pathway and the physiology of blood clotting.
So this kind of elisa kit is crucial in the field of hemophilia research, we DLdevelop can provide the most sensitive and accurate test kit to help the researchers well in this field.

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